abstract：:The liver and spleen both have important phagocytic functions and contain monocytes/macrophages which clear immune complexes. We describe here three patients who presented proteinuria and hematuria 7 to 13 years after portosystemic shunt surgery, which diverted portal venous blood to the systemic circulation. They had...

journal_title：Clinical nephrology

authors： Soma J,Saito T,Sato H,Ootaka T,Abe K

更新日期：1997-11-01 00:00:00

abstract：:A 35-year-old nephrotic man developed acute renal failure with serum creatinine to 1543 micromol/l after a month of therapy with enalapril. Renal biopsy demonstrated minimal glomerular changes with fusion of podocytes, tubular necrosis with regeneration of tubular epithelial cells, interstitial edema with focal inters...

journal_title：Clinical nephrology

authors： Grcevska L,Polenaković M,Dzikova S,Grozdanovski R

更新日期：1997-11-01 00:00:00

abstract：:End-stage renal failure is commonly considered a significant factor for an increased risk after coronary artery bypass grafting. This holds true for patients who have received a kidney transplant (NTX group) as well as for patients who require chronic hemodialysis (HD group). To assess the risk in our population we pe...

journal_title：Clinical nephrology

authors： Christiansen S,Claus M,Philipp T,Reidemeister JC

更新日期：1997-10-01 00:00:00

abstract：:Control of hyperphosphoremia is crucial to the prevention of secondary hyperparathyroidism. Calcium salts of keto-amino acids (KAA) were employed as phosphate binders in hemodialysis patients. We wanted to assess the efficacy of these substances as quelating agents in patients under continuous ambulatory peritoneal di...

journal_title：Clinical nephrology

authors： Macia M,Coronel F,Navarro JF,Gallego E,Herrero JA,Méndez ML,Chahin J,García J

更新日期：1997-09-01 00:00:00

abstract：:The occurrence of kidney diseases was very rarely reported in heavy chain diseases (HCD). At variance with gamma and alpha HCD in which there is no free light chain secretion, about two-thirds of mu HCD patients have urinary Bence Jones (BJ) proteins. We report on a 66 year-old man affected with typical mu HCD who dev...

journal_title：Clinical nephrology

authors： Preud'homme JL,Bauwens M,Dumont G,Goujon JM,Dreyfus B,Touchard G

更新日期：1997-08-01 00:00:00

abstract：:Severe metabolic acidosis in the setting of alcoholism raises diagnostic and therapeutic problems [Levinsky 1994]. Alcoholic ketoacidosis and toxic alcohol ingestion can be difficult to distinguish on initial presentation [Litovitz 1986]. A high osmolal gap associated with increased anion gap acidosis is said to be in...

journal_title：Clinical nephrology

authors： Almaghamsi AM,Yeung CK

更新日期：1997-07-01 00:00:00

abstract：:We studied the effectiveness of CAPD in large patients (> 80 kg) (group B, n = 49) by comparing them to a group of patients whose body weight was 60-80 kg (group A, n = 193). Patients in group B were two years younger (55.4 versus 57.7 years, p < 0.01), were predominantly male (M: F ratio 33/16 vs 84/109) and had slig...

journal_title：Clinical nephrology

authors： Afthentopoulos IE,Oreopoulos DG

更新日期：1997-06-01 00:00:00

abstract：:In a previous study, we found that oral chromium nicotinate overcame sucrose-induced hypertension in spontaneously hypertensive rats (SHR). Accordingly, we examined more chromium compounds to determine if others were more or less effective in regulating blood pressure (BP) of SHR. Since chromium is postulated to be an...

journal_title：Clinical nephrology

authors： Preuss HG,Grojec PL,Lieberman S,Anderson RA

更新日期：1997-05-01 00:00:00

abstract：:The usefulness of formula-derived creatinine clearance (CC) is not well established among the paraplegic population. We prospectively collected 24-hour-urines from paraplegic subjects, obtaining 81 collections from 42 patients over 27 months. After validation, 57 collections were used to obtain measured CC. CCs were a...

journal_title：Clinical nephrology

authors： Thakur V,Reisin E,Solomonow M,Baratta R,Aguilar E,Best R,D'Ambrosia R,Solanky T

更新日期：1997-04-01 00:00:00

abstract：PURPOSE:Drug-related morbidity and mortality are significant problems in the U.S. Recognition and resolution of drug-related problems (DRP) will decrease drug-related morbidity and mortality and promote optimal therapeutic outcomes. It was the objective of this study to identify DRP in hemodialysis outpatients by perfo...

journal_title：Clinical nephrology

authors： Grabe DW,Low CL,Bailie GR,Eisele G

更新日期：1997-02-01 00:00:00

abstract：:To investigate the effects of neutrophil activation during hemodialysis (HD), blood markers of oxygen free radical (OFR) activity were studied. Two groups of HD patients on standard cuprophane treatment were investigated after an overnight fast. In the first group (mean age 68 +/- 8 years; n = 6) vitamin supplementati...

journal_title：Clinical nephrology

authors： Hultqvist M,Hegbrant J,Nilsson-Thorell C,Lindholm T,Nilsson P,Lindén T,Hultqvist-Bengtsson U

更新日期：1997-01-01 00:00:00

abstract：:The objective of our study was to evaluate the effects of subpressor doses of angiotensin II and mild physical stress on renal hemodynamics and urinary albumin excretion (UAE) in a group of young patients with essential hypertension compared to normotensive subjects. Eleven patients (26 +/- 6 years) and ten healthy co...

journal_title：Clinical nephrology

authors： Erley CM,Grau C,Furian TC,Wolf S,Braun N,Risler T

更新日期：1996-11-01 00:00:00

abstract：:A short survey is given on important pathomorphologic renal lesions in diabetics, particularly diabetic glomerulosclerosis including aspects on the development of its alterations. The frequency of renal complications in autopsy material of 400 diabetics is reported as well as the occurrence of typical and atypical les...

journal_title：Clinical nephrology

authors： Ditscherlein G

更新日期：1996-10-01 00:00:00

abstract：:Patients with hyponatremia are exposed to major neurological complications. On the one hand hyponatremia itself produces brain edema, increased intracranial pressure which potentially leads to subsequent neuropathological sequelae or death. On the other hand excessive correction could be followed by development of bra...

journal_title：Clinical nephrology

authors： Soupart A,Decaux G

更新日期：1996-09-01 00:00:00

abstract：:The aim of the study was to investigate plasma and muscle amino acid (AA) levels in children on continuous ambulatory peritoneal dialysis (CAPD) and their relationship to various indices of nutritional status. Ten children with a mean age of 6.4 +/- 5.6 yrs were evaluated. Muscle biopsies and venous blood samples were...

journal_title：Clinical nephrology

authors： Canepa A,Divino Filho JC,Forsberg AM,Perfumo F,Carrea A,Verrina E,Podestá E,Gusmano R,Bergström J

更新日期：1996-08-01 00:00:00

abstract：:To elucidate the possible physiological interaction between growth hormone (GH) and insulin-like growth factor-I (IGF-I) system in human kidney, recombinant human GH (rhGH), which reached a supranormal level of serum GH, was administered, and serum and urinary IGF-I levels were determined in 6 normal men. The first tw...

journal_title：Clinical nephrology

authors： Uemasu J,Fujihara M,Kawasaki H

更新日期：1996-07-01 00:00:00

abstract：:Since October 1988 till July 1995, 35 children (mean age 16 +/- 15.5 months) with classical hemolytic uremic syndrome (HUS) were examined for the presence of verocytotoxin (VT)-producing Escherichia coli (VTEC) infection. Stool samples from all patients were cultured for VTEC strains and tested for free fecal neutrali...

journal_title：Clinical nephrology

authors： Bielaszewska M,Janda J,Blahová K,Feber J,Potuzník V,Soucková A

更新日期：1996-07-01 00:00:00

abstract：:The previous methods to biopsy renal allografts at our institution involved the use of the Franklin-Silverman or Tru-Cut needles. Unfortunately they had a significant rate of post biopsy bleeding secondary to deep penetration when excess force was used to penetrate a tough transplant capsule. Although spring loaded bi...

journal_title：Clinical nephrology

authors： Kovalik EC,Schwab SJ,Gunnells JC,Bowie D,Smith SR

更新日期：1996-06-01 00:00:00

abstract：:Amino acid dialysis solution 1.1% (Nutrineal) contains L-arginine, a substrate for nitric oxide (NO) synthesis. NO causes vasodilation in many organs. To investigate effects of the amino acid dialysis solution on peritoneal permeability and perfusion, standard peritoneal permeability analyses were performed in 10 stab...

journal_title：Clinical nephrology

authors： Douma CE,de Waart DR,Struijk DG,Krediet RT

更新日期：1996-05-01 00:00:00

abstract：:The aim of the present study was to investigate whether the pharmacokinetic profile of cyclosporin A under Sandimmun Optoral compared to Sandimmun has an effect on blood pressure in patients with stable renal allograft function. Twenty-eight patients were randomized into two groups. Two pharmacokinetic profiles (I, II...

journal_title：Clinical nephrology

authors： Schwertfeger E,Keller E,Grotz W,Schollmeyer P,Rump LC

更新日期：1996-05-01 00:00:00

abstract：:To determine the pathogenic role of serotonin (5-HT), we investigated 5-HT metabolism in undergoing hemodialysis (HD). Mean value of platelet 5-HT in patients undergoing HD was significantly lower than that of normal controls (0.22 + or - 0.16 pmol/10(5) platelets versus 0.35 + or - 0.13 pmol/10(5) platelets, p <0.02)...

journal_title：Clinical nephrology

authors： Kanai H,Ishii Y,Maezawa A,Yano S,Naruse T

更新日期：1996-04-01 00:00:00

abstract：:Cross-sectional studies in steady state dialysed chronic end-stage renal failure patients show urea clearance (Kt/V) and total urea excretion (protein catabolic rate) correlate positively. However, urea clearance is total urea excretion divided by BUN. Thus urea clearance and BUN relate reciprocally, and so their math...

journal_title：Clinical nephrology

authors： Baltzan MA,Shoker AA,Baltzan RB,Pylypchuk GB

更新日期：1996-03-01 00:00:00

abstract：:Recent studies indicated that polymorphonuclear leukocytes (PMNL) were primed to produce superoxide (O2-) in various types of glomerulonephritis with a particular importance in IgA nephropathy (IgAN). In this study, we have examined O2- production and receptor expression for the Fc portion of IgA (Fc alpha R) in monoc...

journal_title：Clinical nephrology

authors： Kashem A,Endoh M,Nomoto Y,Sakai H,Nakazawa H

更新日期：1996-01-01 00:00:00

abstract：:Idiopathic acquired sideroblastic anemia is not a common disease. We studied the renal tubular function in such patients. Patients have lower calcium than controls (8.46 mg/dl +/- 0.59 vs 9.16 +/- 0.53). We have highlighted the multiple renal anomalies observed in patients with this type of hemopathy. The serum phosph...

journal_title：Clinical nephrology

authors： Hanson B,Sztern B,Vamos E,Lustman F

更新日期：1995-12-01 00:00:00

abstract：:Plasma lipid peroxidation in noninsulin dependent diabetes mellitus (DM) patients were evaluated in DM patients undergoing hemodialysis (HD) by means of a chemiluminescence-HPLC for the specific determination of phosphatidylcholine hydroperoxide (PCOOH). Thirty-three uremic patients with DM nephropathy, undergoing 12 ...

journal_title：Clinical nephrology

authors： Sanaka T,Takahashi C,Sanaka M,Higuchi C,Shinobe M,Hayasaka Y,Miyazawa T,Ishikawa S,Nihei H,Omori Y

更新日期：1995-11-01 00:00:00

abstract：:Oxidized low-density lipoproteins (LDL) play an important role in the pathogenesis of atherosclerosis. An increased sensitivity of red blood cell membranes to lipid peroxidation has been previously demonstrated in patients with chronic renal failure, suggesting that the antioxidant defence of lipoproteins might be imp...

journal_title：Clinical nephrology

authors： Panzetta O,Cominacini L,Garbin U,Fratta Pasini A,Gammaro L,Bianco F,Davoli A,Campagnola M,De Santis A,Pastorino AM

更新日期：1995-11-01 00:00:00

abstract：:The inter-observer variation of the WHO classification of glomerulonephritis (GN) was studied using Kappa statistics. One hundred renal biopsies were selected with almost equal representation of the following types of GN: minimal change nephropathy, membranous GN, focal proliferative GN, diffuse mesangial proliferativ...

journal_title：Clinical nephrology

authors： Marcussen N,Olsen S,Larsen S,Starklint H,Thomsen OF

更新日期：1995-10-01 00:00:00

abstract：:We conducted an immunohistochemical analysis to investigate the presence of monocyte chemoattractant protein-1 (MCP-1) in normal and diseased human kidneys and the correlation with infiltration of macrophages. A total of 50 renal biopsies were classified according to pathologic diagnosis. The distribution as well as t...

journal_title：Clinical nephrology

authors： Prodjosudjadi W,Gerritsma JS,van Es LA,Daha MR,Bruijn JA

更新日期：1995-09-01 00:00:00

abstract：:Sertraline is an antidepressant which selectively inhibits the neuronal uptake of serotonin in the central nervous system. The pharmacokinetics of sertraline in end-stage renal disease (ESRD) and the effect of hemodialysis on sertraline clearance is unknown. A dose of 100 mg sertraline was administered to two anuric h...

journal_title：Clinical nephrology

authors： Schwenk MH,Verga MA,Wagner JD

更新日期：1995-08-01 00:00:00

abstract：:Determination of marker proteins like albumin and alpha 1-microglobulin allows to differentiate various types of proteinuria in kidney diseases. In the present communication we calculate the degree of tubulointerstitial involvement by quantitation of the tubular marker alpha 1-microglobulin in urine in relation to alb...

journal_title：Clinical nephrology

authors： Hofmann W,Edel H,Guder WG

更新日期：1995-07-01 00:00:00

abstract：:Diabetic nephropathy is characterized by mesangial cell proliferation and expansion of the mesangial matrix. Insulin-like growth factor-1 (IGF-1) increases in the kidney early in experimental diabetes. The effect of IGF-1 on mesangial cell proliferation and synthesis of extracellular matrix (ECM) proteins was examined...

journal_title：Clinical nephrology

authors： Schreiber BD,Hughes ML,Groggel GC

更新日期：1995-06-01 00:00:00

abstract：:The hyperviscosity syndrome is a common problem in patients suffering from IgM paraproteinemia. In this situation cytotoxic chemotherapy alone is insufficient and additional plasma therapy is required. Until recently, conventional plasma exchange was the only plasma therapy available. While this method has proven its ...

journal_title：Clinical nephrology

authors： Höffkes HG,Heemann UW,Teschendorf C,Uppenkamp M,Philipp T

更新日期：1995-05-01 00:00:00

abstract：:In historical studies erythropoietin stimulated bone marrow was shown to produce less stable, macrocytic, "stress erythrocytes". Recent work from our lab suggests that erythropoietin serves as both a growth factor and as a survival factor. To investigate the effects of recombinant human erythropoietin (rHuEPO) on deve...

journal_title：Clinical nephrology

authors： Schwartz AB,Orquiza CS

更新日期：1995-04-01 00:00:00

abstract：:Since 1985, the efficacy of cyclosporin A (CyA) in severe psoriasis has been evaluated in a number of open and controlled studies, all of which have clearly established CyA as an effective antipsoriatic agent. The efficacy of CyA has also provided new insights into the pathophysiology of psoriasis. The effects of CyA ...

journal_title：Clinical nephrology

authors： Zachariae H,Steen Olsen T

更新日期：1995-03-01 00:00:00

abstract：:Piperacillin (Pi) kinetics in patients with acute renal failure treated by continuous arteriovenous hemodialysis (CAVHD) are not known. Therefore, dosing regimens have been based on kinetic data derived from patients with chronic renal failure and principal pharmacokinetic considerations [Reetze-Bonorden et al. 1993]....

journal_title：Clinical nephrology

authors： Keller E,Böhler J,Busse-Grawitz A,Reetze-Bonorden P,Krumme B,Schollmeyer P

更新日期：1995-01-01 00:00:00

abstract：:This multicenter study investigated the characteristics of circulating IgA molecules in 77 children: 42 had primary IgA nephropathy (IgAN), 20 were non-IgA glomerulonephritides (CGN) and 15 had urological problems (U). Fifteen assays were employed including the detection of macromolecular IgA [IgA immune complexes (Ig...

journal_title：Clinical nephrology

authors： Coppo R,Amore A,Gianoglio B,Porcellini MG,Peruzzi L,Gusmano R,Giani M,Sereni F,Gianviti A,Rizzoni G

更新日期：1995-01-01 00:00:00

abstract：:During inflammation, activated vascular endothelial cells and other cell types express various adhesion molecules which facilitate binding of circulating leukocytes. Serum concentration of circulating adhesion molecule ICAM-1 (c-ICAM-1) is supposed to reflect the degree of this activation. In order to evaluate the use...

journal_title：Clinical nephrology

authors： John S,Neumayer HH,Weber M

更新日期：1994-12-01 00:00:00

abstract：:We experienced three cases of malignant hypertension. Plasma endothelin-1 (ET-1) was extremely high in all patients on admission (12.1 +/- 1.0 pg/ml, normal 1.5 +/- 0.5 pg/ml), and changed in parallel with the serum creatinine level. In one patient, during the recovery period, serum creatinine increased 1 mg/dl over a...

journal_title：Clinical nephrology

authors： Yoshida M,Nonoguchi H,Owada A,Ishiyama S,Maeda Y,Ando K,Iwamoto H,Shiigai T,Marumo F,Tomita K

更新日期：1994-11-01 00:00:00

abstract：:This case study reveals an unusual finding of rapidly proliferative crescentic glomerulonephritis in a patient treated with rifampin who had no other identifiable causes for developing this disease. This patient underwent a 10-month regimen of rifampin and isoniazid for pulmonary tuberculosis and was discovered to hav...

journal_title：Clinical nephrology

authors： Kohler LJ,Gohara AF,Hamilton RW,Reeves RS

更新日期：1994-10-01 00:00:00

abstract：:Hemoccult test was performed on stool specimens of 249 patients; 64 with advanced renal failure prior to dialysis (CRF), 144 on maintenance hemodialysis (HD), and 41 receiving chronic ambulatory peritoneal dialysis CAPD. Each patient collected spontaneously evacuated stool specimens on three different days. None of th...

journal_title：Clinical nephrology

authors： Akmal M,Sawelson S,Karubian F,Gadallah M

更新日期：1994-09-01 00:00:00